Latest News
Stay informed with the latest updates and awards from Oxford Foot Ankle Research Team. Our team is dedicated to providing exceptional care and innovative treatments for foot and ankle conditions. We are committed to excellence in orthopaedic surgery, ensuring the best outcomes for our patients.
Congratulations to FAROx team and Conor Hennessy for winning the best in class paper at the American Academy of Orthopaedic Surgeons - AAOS 2025!
Congratulations to FAROx team for winning the Chang Cheng Memorial Prize at BOFAS!
Thank you Mark Davies for BOFAS 2025 and Rick Brown for collecting the Prize. Well done Conor Hennessy for your work on
Mortality, re-amputation and post operative complication rates following 28,000 below knee amputation in diabetic patients in England: a national population study 2002-2022.
ABOUT US
Welcome to the Foot Ankle Research Group Oxford (FAROx). We are a team of dedicated researchers and medical professionals committed to advancing the field of foot and ankle care.
Our mission is to provide the highest research and education to improve the lives of patients with foot and ankle conditions.
Thank you for visiting our website and we look forward to sharing our work with you.
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The use of Patient Reported Outcome Measures to improve delivery of elective foot ankle surgery
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Improving outcomes in foot and ankle bone infection surgery
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Mortality, re-amputation and post operative complication rates following 28,000 below knee amputations in diabetic patients in England: a national population study 2002-2022. (BOFAS sponsored trial)
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Understanding ankle arthritis, causes and cures, in the UK population
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Gender differences in foot and ankle sporting injuries
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Predicting the risks of Malignancy of Bone and Soft Tissue Tumours of the Foot and Ankle - OxFAT (Oxford Foot and Ankle Tumour) Score
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The role of PTX3+ human tendon cells in chronic Achilles tendon disease
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Improved outcomes in Foot and Ankle bone infection
OUR PROJECTS
RESEARCH TEAM
Adrian Kendal
MA (Oxon.) BMBCh, DPhil (Oxon.), FRCS (Ortho.)
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Honorary Senior Clinical Lecturer, University Of Oxford
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Specialist Orthopaedic Surgeon with subspecialty interest in Foot and Ankle Reconstruction
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Lecturer at Trinity College, Oxford
Adrian's research aim is to understand the pathogenesis of chronic debilitating tendon disease. Tendon disease accounts for over 20% of primary care consultations and represents a growing healthcare challenge in an active and increasingly ageing population. Recognising critical cells involved in tendinopathy is essential in developing therapeutics to meet this challenge.
Adrian has applied combined single cell transcriptomics and surface proteomics to identify novel tendon cell sub-types in diseased and healthy human tendon. For the first time, he has shown that human tendon harbours multiple distinct COL1A1/2 expressing tenocyte populations in addition to endothelial cells, T-cells, and monocytes. Adrian is interested in the temporal-spatial interaction of particular tendon cell sub-types in the pathogenesis of chronic tendinopathy, for example pro-inflammatory PTX3 cells and signalling pathways.
Conor Hennessy
MB BcH University of Oxford.
BsC, Biomedical Science NUI Galway.
PhD NUI Galway
Conor was a PhD student in the Pharmacology and Therapeutics department of NUI Galway. His project was focused on the epigenetic regulation of the viral receptor TLR3 and how altering its regulation affects viral immunology.
Conor has a strong background in science having completed his undergrad in Biomedical science in NUI Galway. Conor is trained in number of analytical techniques, including PCR, flow cytometry cell culture based assays, toxicological and cell death assays as well as others.
He has recently completed an AFP in advanced population database analytics of orthopaedic interventions.
Orthopaedic Research Surgeons
Rick Brown
Bob Sharp
Con Loizou
Research Nurse Specialists
Martin Austin
Current and Previous Medical Students
Ibrahem Al-Obaidi
Arun Somanathan
Ben George
Charlotte Cossins
Jesse Kimani
Our publications
Hennessy, C., et al., Mortality and Re-Amputation Rates Following Below Knee Amputation: A Systematic Review and Meta-Analysis. British Journal of Surgery, 2024. 111.
Woods, A., et al., Association of Preexisting Triple Fusion and Arthroscopic Ankle Arthrodesis nonunion. Foot & Ankle International, 2023. 44(7): p. 579-586.
Cherief, M., et al., TrkA-mediated sensory innervation of injured mouse tendon supports tendon sheath progenitor cell expansion and tendon repair. Science Translational Medicine, 2023. 15(727).
Sharma, A., et al., The Application and Patient-Reported Experience of Telephone Consultations in Elective Foot and Ankle Orthopaedic Surgery: 12-Month Follow-up. Foot & Ankle International, 2022. 43(5): p. 694-702.
Gomez-Collignon, A., et al., SINGLE-CELL MULTI-OMICS CHARACTERISE DISCRETE HUMAN TENDON CELLS POPULATIONS THAT PERSIST <i>IN VITRO</i> AND ON FIBROUS SCAFFOLDS. European Cells & Materials, 2022. 44: p. 1-20.
Kendal, A.R., et al., Multi-omic single cell analysis resolves novel stromal cell populations in healthy and diseased human tendon. Scientific Reports, 2020. 10(1).
Kendal, A., et al., RESORBABLE ELECTROSPUN POLYDIOXANONE FIBRES MODIFY THE BEHAVIOUR OF CELLS FROM BOTH HEALTHY AND DISEASED HUMAN TENDONS. European Cells & Materials, 2017. 33: p. 169-182.
Kendal, A.R., et al., Mortality rates at 10 years after metal-on-metal hip resurfacing compared with total hip replacement in England. British Journal of Sports Medicine, 2016. 50(3): p. 187-187.
Hilbrands, R., et al., Induced Foxp3<SUP>+</SUP> T Cells Colonizing Tolerated Allografts Exhibit the Hypomethylation Pattern Typical of Mature Regulatory T Cells. Frontiers in Immunology, 2016. 7.
Foulke, B.A., et al., Fracture healing in the elderly: A review. Maturitas, 2016. 92: p. 49-55.
Kendal, A.R., et al., Complications of Minimally Invasive Calcaneal Osteotomy Versus Open Osteotomy. Foot & Ankle International, 2015. 36(6): p. 685-690.
Kendal, A.R., P. Cooke, and R. Sharp, Arthroscopic Ankle Fusion for Avascular Necrosis of the Talus. Foot & Ankle International, 2015. 36(5): p. 591-597.
Kendal, A., Unintended consequences: might major surgery accelerate cancer? Reply. Bmj-British Medical Journal, 2014. 348.
Regateiro, F.S., et al., The induction of transplantation tissue tolerance requires Foxp3 expression. Allergy, 2013. 68: p. 181-181.
Kendal, A.R., et al., Mortality rates at 10 years after metal-on-metal hip resurfacing compared with total hip replacement in England: retrospective cohort analysis of hospital episode statistics. Bmj-British Medical Journal, 2013. 347.
Funding bodies
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BOFAS
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Royal College Surgeons
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Medical Sciences Division, Oxford